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PUBLICATIONS


Diabetes: Stem Cells Offering Healthy Promises
LSaraswat A, Srivastava A. J Stem Cell Res Ther. 2018 May, 4(3):46-47. Editorial Diabetes is a chronic lifelong disease and according to Diabetes Association of America, in 2015 itself approximately 30.3million Americans (9.4% of the population) have the disease. Unfortunately, almost one fourth (or approximately 7.2million) are unaware that they have it. An additional 84.1million people have pre-diabetes. With increasing prosperity, its prevalence has increased in almost all
hiyadigi
Jul 212 min read


Role Of Cell Based Approaches In Cancer Immunotherapy
Mahmood A, Srivastava A, Srivastava S, Pandya H, Neel Khokhani, Divyang Patel, Rangnath Mishra. J Stem Cell Res Ther. May 2017, 2(5): 00077. Abstract Immunotherapies hold the potential for cancer treatment since their mode of action is distinct to chemo and radiation therapy and largely depends on harnessing body’s own immune system. The major advantage associated with cancer immunotherapy is that cell responses are specific to tumor and with low or negligible toxicity. Precl
hiyadigi
Jul 211 min read


Inflammatory Bowel Diseases: Current Therapeutic Approaches And Potential Of Using Stem Cells
Mishra T, Sarswat A, Mishra K, Srivastava AS. J Stem Cell Res Ther. 2017 Feb. 2(2): 00057. Abstract Inflammatory bowel diseases (IBDs) are chronic and progressively deteriorating in nature without many promising curative treatments. Chronic inflammation of not well defined origins is considered to be the root cause of the problem which affects intestinal mucosa with or without transmural involvement. IBDs are divided in two main categories: Crohn’s disease (CD) and ulcerative
hiyadigi
Jul 212 min read


Mesenchymal Stem Cell Conditioned Media Ameliorate Psoriasis Vulgaris
Seetharaman R, Mahmood A, Kshatriya P, Patel D, Srivastava A. Case Reports in Dermatological Medicine. May 2019; Introduction Psoriasis is a chronic disease thought to be of autoimmune origin which is characterized by patches on the skin and nails. It has been considered as a serious skin related problem affecting approximately 100 million individuals worldwide. About 2% of the world population and 0.44-2.8% of the Indian population were affected by psoriasis in 2016-2017 [1,
hiyadigi
Jul 213 min read


Cardiovascular Diseases: Recent Developments In Regenerative Medicine
Mahmood, A., Pandya, H., Rajasekar,S., Patel, D., Srivastava A.. Journal of Stem Cell Research & Therapeutics. 2017, July 3(2):00095. doi: 10.15406/jsrt.2017.03.00095. Abstract Advent of regenerative medicine has opened new therapeutic interventions for patients with cardiovascular diseases. The stem cell based cardiac repairing and regeneration along with improved vascularisation can improve diseased heart. Clinical studies over last decade have evaluated the cardiogenic pot
hiyadigi
Jul 211 min read


Mannose supplements induce embryonic lethality and blindness in phosphomannose isomerase hypomorphic mice
Sharma V, Nayak J, DeRossi C, Charbono A, Ichikawa M, Ng BG, Grajales-Esquivel E, Srivastava A, Wang L, He P, Scott DA, Russell J, Contreras E, Guess CM, Krajewski S, Del Rio-Tsonis K, Freeze HH. FASEB J. 2014 Apr 28(4):1854-69. doi: 10.1096/fj.13-245514. Abstract Patients with congenital disorder of glycosylation (CDG), type Ib (MPI-CDG or CDG-Ib) have mutations in phosphomannose isomerase (MPI) that impair glycosylation and lead to stunted growth, liver dysfunction, coagulo
hiyadigi
Jul 211 min read
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